SCHEMBL2556842

SCHEMBL2556842

[CH2]Cc1ccc(CCc2cnc3c(N)nc4cc(C)ccc4c3c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008618 0.93 TLR7 (0.60) TLR7
SCHEMBL1062753 0.90 TLR7 (0.58) TLR7
SCHEMBL1063261 0.89 TLR7 (0.57) TLR7
SCHEMBL1060132 0.89 TLR7 (0.57) TLR7
SCHEMBL1061401 0.89 TLR7 (0.57) TLR7
SCHEMBL16735823 0.89 TLR7 (0.54) TLR7
SCHEMBL1008692 0.88 TLR7 (0.56) TLR7
SCHEMBL1064056 0.88 TLR7 (0.59) TLR7
SCHEMBL1062718 0.88 TLR7 (0.59) TLR7
SCHEMBL18752925 0.88 TLR7 (0.56) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011130379-A1 BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF NOVARTIS AG (CH) 2011-10-20 WO disclosed