Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704945 | 0.87 | HTT (0.62) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL20412826 | 0.86 | HRH3 (0.63) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL14417946 | 0.86 | KDM4E (0.72) | ALDH1A1KDM4EHTTLMNAPOLB | |
| SCHEMBL18704957 | 0.85 | HTT (0.66) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL18389971 | 0.84 | KDM4E (0.74) | ALDH1A1KDM4EHRH3HTTLMNA | |
| SCHEMBL18389940 | 0.84 | HRH3 (0.50) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL16083487 | 0.84 | MAPK1 (0.51) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL18704954 | 0.84 | HRH3 (0.50) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL24600470 | 0.83 | HTT (0.62) | ALDH1A1KDM4EHRH3CYP2D6HTT | |
| SCHEMBL18389927 | 0.83 | SMN1; SMN2 (0.50) | ALDH1A1HRH3CYP2D6HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |