Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18427337 | 1.00 | CARM1 (0.48) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL29860764 | 0.89 | HSD17B10 (0.55) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL681608 | 0.87 | CARM1 (0.62) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL845511 | 0.87 | HSD17B10 (0.57) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL14980614 | 0.84 | HSD17B10 (0.47) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL13078379 | 0.84 | HSD17B10 (0.47) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL19147880 | 0.83 | CARM1 (0.62) | CARM1PRMT6PRMT8PRMT1ACE2 | |
| SCHEMBL18427294 | 0.83 | CARM1 (0.40) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL22416418 | 0.82 | HSD17B10 (0.48) | CARM1PRMT6PRMT8HSD17B10CYP3A4 | |
| SCHEMBL18427295 | 0.81 | HSD17B10 (0.36) | CARM1PRMT6PRMT8HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |