Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 19/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | GPR183 | P32249 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | APLNR | P35414 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25570706 | 0.89 | HTR2A (0.78) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL25570686 | 0.88 | HTR2A (0.76) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL25570697 | 0.87 | HTR2A (0.84) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL3716947 | 0.86 | HTR2A (0.73) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL25571423 | 0.86 | HTR2A (0.80) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL3946052 | 0.86 | HTR2A (1.00) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL6203023 | 0.86 | HTR2A (1.00) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL4096940 | 0.85 | HTR2A (1.00) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL25570733 | 0.85 | HTR2A (0.66) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 | |
| SCHEMBL3719346 | 0.84 | HTR2A (0.70) | HTR2ACYP1A2HTR2CCYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186893-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Geneora Pharma (Shijiazhuang) Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |