Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.31 |
| ▸ | GRM6 | O15303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924574 | 0.76 | POLB (1.00) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL2348382 | 0.74 | POLB (0.56) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL3278963 | 0.72 | POLB (0.55) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL13390131 | 0.70 | POLB (0.75) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL106105 | 0.70 | POLB (0.65) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL15507332 | 0.68 | POLB (0.80) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL4431651 | 0.68 | POLB (0.71) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL4431653 | 0.68 | POLB (0.71) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL6737476 | 0.68 | POLB (0.50) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL19285910 | 0.68 | POLB (0.50) | POLBTDP1CTDSP1APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |