Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 18/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953582 | 0.92 | KDM4E (0.62) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29950907 | 0.92 | KDM4E (0.62) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2560235 | 0.92 | KDM4E (0.62) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2558768 | 0.92 | GAA (0.78) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL23382111 | 0.85 | GAA (0.65) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2558052 | 0.81 | NOTUM (0.68) | NOTUMKDM4E | |
| SCHEMBL16110168 | 0.80 | NOTUM (0.76) | NOTUM | |
| SCHEMBL13622662 | 0.80 | GAA (0.67) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2560204 | 0.79 | NOTUM (0.59) | GAANOTUMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2560607 | 0.79 | NOTUM (0.48) | GAANOTUMKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |