Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575194 | 0.91 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL29374313 | 0.91 | TLR7 (0.54) | TLR7TLR8DHFR | |
| SCHEMBL3861399 | 0.91 | TLR7 (0.54) | TLR7TLR8DHFR | |
| SCHEMBL3860807 | 0.91 | TLR7 (0.54) | TLR7TLR8DHFR | |
| SCHEMBL3860817 | 0.91 | TLR7 (0.54) | TLR7TLR8DHFR | |
| SCHEMBL2113100 | 0.84 | TLR7 (0.52) | TLR7TLR8DHFRNLRP3 | |
| SCHEMBL483282 | 0.83 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL30346099 | 0.83 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL3861633 | 0.83 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL2115601 | 0.83 | TLR7 (0.55) | TLR7TLR8DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166640-B1 | COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-06-14 | — | — | EP | disclosed |