Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575994 | 0.85 | CRBN (0.51) | CRBNDDB1IDO1 | |
| SCHEMBL25905904 | 0.83 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL25575969 | 0.82 | CRBN (0.56) | CRBNDDB1IDO1 | |
| SCHEMBL25575943 | 0.81 | CRBN (0.68) | CRBNDDB1IDO1 | |
| SCHEMBL27114739 | 0.81 | CRBN (0.49) | CRBNDDB1IDO1 | |
| SCHEMBL25575908 | 0.80 | DDB1 (0.61) | CRBNDDB1 | |
| SCHEMBL24319159 | 0.79 | DDB1 (0.56) | CRBNDDB1IDO1 | |
| SCHEMBL25920712 | 0.79 | CRBN (0.56) | CRBNDDB1IDO1 | |
| SCHEMBL25575940 | 0.77 | CRBN (0.54) | CRBNDDB1IDO1 | |
| SCHEMBL25955986 | 0.76 | DDB1 (0.47) | CRBNDDB1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |