Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155880 | 0.86 | DYRK1A (0.48) | DYRK1A | |
| SCHEMBL21155884 | 0.83 | DYRK1A (0.50) | DYRK1A | |
| SCHEMBL21156812 | 0.83 | DYRK1A (0.49) | DYRK1A | |
| SCHEMBL21155877 | 0.83 | DYRK1A (0.47) | DYRK1A | |
| SCHEMBL21155878 | 0.83 | DYRK1A (0.46) | DYRK1A | |
| SCHEMBL21155867 | 0.82 | DYRK1A (0.53) | DYRK1A | |
| SCHEMBL21155881 | 0.81 | DYRK1A (0.46) | DYRK1A | |
| SCHEMBL21156809 | 0.81 | DYRK1A (0.50) | DYRK1A | |
| SCHEMBL21156808 | 0.81 | DYRK1A (0.53) | DYRK1A | |
| SCHEMBL21156283 | 0.80 | DYRK1A (0.54) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717475-B1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL MED MOUNT SINAI (US) | 2023-06-07 | — | — | EP | disclosed |