Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 14/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | IL1B | P01584 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.42 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25582890 | 0.95 | CRBN (0.54) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL30936969 | 0.87 | CRBN (0.53) | CRBNIKZF1IKZF3DDB1TNF | |
| SCHEMBL24816683 | 0.85 | CRBN (0.49) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL19585186 | 0.85 | CRBN (0.55) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL25582896 | 0.84 | CRBN (0.56) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL25036520 | 0.83 | CRBN (0.59) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL30936833 | 0.83 | STAT3 (0.52) | CRBNIKZF1IKZF3DDB1TNF | |
| SCHEMBL31129754 | 0.83 | CRBN (0.52) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL25034761 | 0.83 | CRBN (0.52) | CRBNCSNK1A1IKZF1IKZF3DDB1 | |
| SCHEMBL29790775 | 0.83 | CRBN (0.58) | CRBNIKZF1IKZF3DDB1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088245-A1 | DEGRADATION AGENT AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-05-25 | — | — | WO | disclosed |