Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.73 |
| ▸ | CCNK | O75909 | 19/20 | 0.73 |
| ▸ | CDK9 | P50750 | 19/20 | 0.73 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.73 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.73 |
| ▸ | CDK2 | P24941 | 16/20 | 0.73 |
| ▸ | CDK7 | P50613 | 6/20 | 0.72 |
| ▸ | CCNH | P51946 | 6/20 | 0.72 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25581197 | 0.94 | CCNT1 (0.69) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25580517 | 0.93 | CCNT1 (0.74) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25581947 | 0.92 | CCNT1 (0.70) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25591588 | 0.91 | CDK7 (0.64) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25596340 | 0.91 | CDK7 (0.64) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25581196 | 0.91 | CCNT1 (0.66) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25594915 | 0.90 | CDK7 (0.63) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25594909 | 0.90 | CDK7 (0.63) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25581200 | 0.88 | CCNT1 (0.68) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25596448 | 0.85 | CCNT1 (0.68) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078451-A1 | COMPOUND USED AS CDK7 KINASE INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-05-11 | — | — | WO | disclosed |