Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17132189 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL17132190 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL305092 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL26073653 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2MGAMGAASIMGAM2 | |
| Malic Acid SCHEMBL29124821 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL8653303 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL891003 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4388130 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL122314 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL11314767 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128699-A2 | NOVEL PROCESS | GENERICS [UK] LIMITED (GB) | 2011-10-20 | — | — | WO | disclosed |