Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 0.57 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.57 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672074 | 0.87 | P2RY1 (0.56) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL16368322 | 0.87 | P2RY1 (0.56) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL16644376 | 0.87 | P2RY1 (0.58) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL16374101 | 0.87 | P2RY1 (0.56) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL23171662 | 0.83 | P2RY1 (0.59) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL16368363 | 0.83 | P2RY1 (0.59) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL17384915 | 0.82 | P2RY1 (0.64) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL16368340 | 0.82 | P2RY1 (0.55) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL25566017 | 0.82 | ADORA2A (0.44) | P2RY1P2RY2P2RY11P2RX1P2RX3 | |
| SCHEMBL21078487 | 0.81 | P2RY1 (0.59) | P2RY1P2RY2P2RY11P2RX1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |