SCHEMBL25588138

SCHEMBL25588138

CC(C)(C)n1cc(-c2ccc(O)c(N3CC(=O)NS3(=O)=O)c2F)cn1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 18/20 0.44
PTPN1 P18031 7/20 0.43
BRD4 O60885 1/20 0.37
EP300 Q09472 1/20 0.37
CREBBP Q92793 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31328082 1.00 PTPN2 (0.44) PTPN2PTPN1BRD4EP300CREBBP
SCHEMBL25585325 0.93 PTPN2 (0.43) PTPN2PTPN1
SCHEMBL25587963 0.91 PTPN2 (0.44) PTPN2PTPN1
SCHEMBL25585301 0.89 PTPN2 (0.42) PTPN2PTPN1
SCHEMBL25587786 0.88 PTPN2 (0.49) PTPN2PTPN1
SCHEMBL25588963 0.87 PTPN2 (0.41) PTPN2PTPN1
SCHEMBL31328171 0.84 PTPN2 (0.47) PTPN2PTPN1
SCHEMBL25585323 0.84 PTPN2 (0.47) PTPN2PTPN1
SCHEMBL25584505 0.84 PTPN2 (0.47) PTPN2PTPN1
SCHEMBL31328147 0.83 PTPN2 (0.44) PTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096928-A1 HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. (US) 2023-06-01 WO disclosed