Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.50 |
| ▸ | ATF1 | P18846 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | XPO1 | O14980 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590568 | 0.80 | ABL1 (0.47) | MCHR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25210996 | 0.80 | AHR (0.56) | KCNQ3KCNQ2KCNE1KCNQ1ATF1 | |
| SCHEMBL30184161 | 0.80 | KCNQ3 (0.54) | KCNQ3KCNQ2KCNE1KCNQ1ATF1 | |
| SCHEMBL25257907 | 0.80 | KCNQ3 (0.54) | KCNQ3KCNQ2KCNE1KCNQ1ATF1 | |
| SCHEMBL25245163 | 0.79 | KCNQ3 (0.48) | KCNQ3KCNQ2KCNE1KCNQ1ATF1 | |
| SCHEMBL25247883 | 0.77 | MCHR1 (0.48) | MCHR1TRPV1 | |
| SCHEMBL16586318 | 0.74 | AHR (0.50) | KCNQ3KCNQ2KCNE1KCNQ1ATF1 | |
| SCHEMBL17448401 | 0.71 | POLB (0.64) | ATF1NFKB1AHRNPC1RAB9A | |
| SCHEMBL25381414 | 0.71 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18070920 | 0.70 | MAPT (0.61) | KCNQ3KCNQ2KCNE1KCNQ1ATF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |