Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843572 | 1.00 | VHL (0.38) | VHL | |
| SCHEMBL25592531 | 0.78 | CYP2A6 (0.37) | — | |
| SCHEMBL25592546 | 0.76 | VHL (0.39) | VHL | |
| SCHEMBL24017054 | 0.73 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL4935498 | 0.73 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL30725825 | 0.73 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL4935506 | 0.73 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL30725833 | 0.73 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL25326548 | 0.72 | DYRK1A (0.36) | — | |
| SCHEMBL25326717 | 0.72 | DYRK1A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099620-A1 | KRAS DEGRADING COMPOUNDS COMPRISING ANNULATED 2-AMINO-3-CYANO THIOPHENES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-08 | — | — | WO | disclosed |