Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 1.00 |
| ▸ | LCK | P06239 | 18/20 | 1.00 |
| ▸ | BTK | Q06187 | 4/20 | 1.00 |
| ▸ | EGFR | P00533 | 10/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16765129 | 1.00 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL16765130 | 1.00 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL31039877 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL21855159 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL28642729 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL21855218 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL21947754 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL21946330 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL32670362 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL28642920 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |