Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 18/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.49 |
| ▸ | CDK2 | P24941 | 15/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.49 |
| ▸ | CDK9 | P50750 | 13/20 | 0.49 |
| ▸ | CDK7 | P50613 | 11/20 | 0.49 |
| ▸ | CCNH | P51946 | 11/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25594623 | 0.94 | CCNK (0.48) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL25594676 | 0.90 | CDK7 (0.48) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL25594622 | 0.90 | CCNK (0.52) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL24588151 | 0.89 | CCNK (0.63) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL28817272 | 0.87 | CCNK (0.63) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL28817273 | 0.87 | CCNK (0.63) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL24588967 | 0.86 | CCNK (0.67) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL25595551 | 0.85 | CDK7 (0.48) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL25596476 | 0.85 | CDK7 (0.48) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL24583163 | 0.85 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186895-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | TYK Medicines Inc. (CN) | 2023-05-31 | — | — | EP | disclosed |