Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FTH1 | P02794 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108599 | 0.83 | — | — | |
| SCHEMBL1262673 | 0.83 | — | — | |
| SCHEMBL14087223 | 0.83 | — | — | |
| SCHEMBL19256280 | 0.81 | — | — | |
| SCHEMBL55792 | 0.80 | — | — | |
| SCHEMBL15471499 | 0.80 | — | — | |
| Methyl Alcohol SCHEMBL3833898 | 0.79 | CYP3A4 (0.43) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| Chloromethane SCHEMBL4688989 | 0.79 | CYP3A4 (0.39) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL11177573 | 0.70 | CYP3A4 (0.55) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL15484174 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174548-A1 | SYMBIOTIC PRODRUGS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174548-A1 | SYMBIOTIC PRODRUGS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | NFKBIA, NFRKB, IKBKB | CYP3A4 2771/4885ALDH1A1 2443/4885FTH1 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.