Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 13/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938356 | 0.89 | MAPK3 (0.51) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL15938357 | 0.89 | MAPK3 (0.51) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL30398019 | 0.85 | TRPV1 (0.46) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL25531479 | 0.85 | TRPV1 (0.46) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL24704507 | 0.83 | MAPK3 (0.52) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL28543270 | 0.83 | MAPK3 (0.52) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL29647980 | 0.83 | MAPK3 (0.52) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL25596868 | 0.83 | MAPK3 (0.46) | TRPV1MAPK3HDAC4HDAC6USP30 | |
| SCHEMBL28729828 | 0.82 | MAPK3 (0.58) | MAPK3USP30IDH1 | |
| SCHEMBL29647993 | 0.82 | MAPK3 (0.58) | MAPK3USP30IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |