Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.82 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177513 | 0.90 | S1PR1 (1.00) | S1PR1S1PR3BCHEACHEMAP4K4 | |
| SCHEMBL29410964 | 0.90 | S1PR1 (1.00) | S1PR1S1PR3BCHEACHEMAP4K4 | |
| SCHEMBL26004417 | 0.88 | S1PR1 (0.95) | S1PR1S1PR3BCHEACHEMAP4K4 | |
| SCHEMBL15662160 | 0.86 | S1PR1 (0.91) | S1PR1S1PR3BCHEACHEMAP4K4 | |
| SCHEMBL15662886 | 0.84 | S1PR1 (0.88) | S1PR1S1PR3BCHEACHEMAP4K4 | |
| SCHEMBL15703942 | 0.83 | S1PR1 (0.70) | S1PR1S1PR3 | |
| SCHEMBL9996208 | 0.83 | S1PR1 (0.86) | S1PR1S1PR3SMN1; SMN2 | |
| SCHEMBL15662515 | 0.81 | S1PR1 (0.82) | S1PR1S1PR3MAP4K4PRKCDMINK1 | |
| SCHEMBL177230 | 0.80 | S1PR1 (0.82) | S1PR1S1PR3SMN1; SMN2 | |
| SCHEMBL15661823 | 0.80 | S1PR1 (0.82) | S1PR1S1PR3MAP4K4PRKCDMINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723801-B1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR | BIORA THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |