SCHEMBL255980

SCHEMBL255980

C=C/C=C\C=C/N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13216035 1.00
SCHEMBL13579995 1.00
SCHEMBL28062089 1.00
SCHEMBL23534427 1.00
SCHEMBL3033738 1.00
SCHEMBL23299485 1.00
SCHEMBL18055760 1.00
SCHEMBL548169 0.84
SCHEMBL548168 0.84
SCHEMBL8282143 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233413-A1 eIF4G1-eIF1 INHIBITORS AND USE THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-12-07 WO disclosed
US-20230217805-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-11566015-B2 Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof Crinetics Pharmaceuticals, Inc. (US) 2023-01-31 US disclosed
EP-3183236-B1 METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WSS (DE) 2022-04-20 EP disclosed
US-11090247-B2 Compositions for protecting the skin from heavy metals and formaldehyde FNG RESEARCH CO., LTD. (KR) 2021-08-17 US disclosed
US-20210238164-A1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. 2021-08-05 US disclosed
US-20210207064-A1 COMPOUND FOR RESTORING CONTAMINATED SOIL OR CONTAMINATED WATER FNG RESEARCH CO., LTD. (KR) 2021-07-08 US disclosed
EP-3286181-B1 PYRAZOLE COMPOUNDS AND METHOD FOR MAKING AND USING THE COMPOUNDS RIGEL PHARMACEUTICALS INC (US) 2021-01-27 EP disclosed
US-10189774-B2 High penetration prodrug compositions of mustards and mustard-related compounds TECHFIELDS PHARMA CO., LTD. (CN) 2019-01-29 US disclosed
US-10017481-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2018-07-10 US disclosed
WO-2008125589-A2 TRIS(HETEROCYCLYL) METAL COMPLEXES AS BLEACH CATALYSTS HENKEL AG & CO. KGAA (DE) 2008-10-23 WO disclosed
WO-2008107436-A1 BICYCLIC ORGANIC COMPOUNDS SUITABLE FOR THE TREATMENT OF INFLAMMATORY OR ALLERGIC CONDITIONS NOVARTIS AG (CH) 2008-09-12 WO disclosed
WO-2008104994-A2 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) 2008-09-04 WO disclosed
EP-1465626-B1 PHARMACEUTICAL COMPOSITIONS (KIT) COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY (OR AN ANTIINFLAMMATORY) AGENT AND THEIR USES EISAI R&D MAN CO LTD (JP) 2008-09-03 EP disclosed
WO-2008098368-A1 INHIBITORS OF HEPATITIS C NS3 PROTEASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-08-21 WO disclosed
EP-1598048-B1 Composition for coloring of keratin fibres KPSS KAO GMBH (DE) 2008-08-13 EP disclosed
EP-1166753-B1 Hair dye composition KAO CORP (JP) 2008-03-05 EP disclosed
EP-1854638-A1 Reversible thermosensitive coloring material and reversible thermosensitive recording material using the same Ricoh Company, Ltd. (JP) 2007-11-14 EP disclosed
WO-2007051065-A2 COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE NUMERATE, INC. (US) 2007-05-03 WO disclosed
WO-2006086609-A2 INHIBITORS OF TRYPTASE AXYS PHARMACEUTICALS, INC. (US) 2006-08-17 WO disclosed