Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254673 | 0.92 | NAMPT (0.33) | NFKB1NFKB2RELANAMPTTRAP1 | |
| SCHEMBL30377635 | 0.92 | NAMPT (0.33) | NFKB1NFKB2RELANAMPTTRAP1 | |
| SCHEMBL30377606 | 0.84 | NAMPT (0.34) | NAMPTTRAP1HSP90B1HSP90AA1 | |
| SCHEMBL25250614 | 0.84 | NAMPT (0.34) | NAMPTTRAP1HSP90B1HSP90AA1 | |
| SCHEMBL25253982 | 0.83 | EGFR (0.38) | ACKR3 | |
| SCHEMBL30377663 | 0.83 | EGFR (0.38) | ACKR3 | |
| SCHEMBL25244269 | 0.82 | EGFR (0.38) | — | |
| SCHEMBL30377390 | 0.82 | EGFR (0.38) | — | |
| SCHEMBL25214030 | 0.82 | EGFR (0.37) | ACKR3 | |
| SCHEMBL30378144 | 0.82 | EGFR (0.37) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094834-A1 | ISOINDOLINES AS PMS2 INHIBITORS | Neophore Limited (GB) | 2023-06-01 | — | — | WO | disclosed |