Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447033 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL30591264 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL4300466 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL28190777 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL3599330 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL19602568 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL20636626 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL644549 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL17694369 | 0.75 | CYP3A4 (0.53) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL17494321 | 0.75 | SOS1 (0.44) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098876-A1 | CARBONYL SUBSTITUTED DIAZASPIRO COMPOUNDS AND ITS USE | BIONOVA PHARMACEUTICALS (SHANGHAI) LIMITED (CN) | 2023-06-08 | — | — | WO | disclosed |