Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.76 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.73 |
| ▸ | KDR | P35968 | 2/20 | 0.73 |
| ▸ | BRAF | P15056 | 2/20 | 0.73 |
| ▸ | CIT | O14578 | 1/20 | 0.73 |
| ▸ | GAK | O14976 | 1/20 | 0.73 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.73 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.73 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.73 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.73 |
| ▸ | STK17B | O94768 | 1/20 | 0.73 |
| ▸ | STK10 | O94804 | 1/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.73 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.73 |
| ▸ | ABL1 | P00519 | 1/20 | 0.73 |
| ▸ | LCK | P06239 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17557997 | 0.94 | EGFR (0.71) | EGFRERBB2KDRBRAFCIT | |
| SCHEMBL643027 | 0.90 | EGFR (0.79) | EGFRERBB2KDRFLT4EPHB4 | |
| SCHEMBL4226041 | 0.89 | EGFR (0.81) | EGFRERBB2KDRBRAFCIT | |
| SCHEMBL17557989 | 0.89 | EGFR (0.71) | EGFRERBB2KDRBRAFCIT | |
| SCHEMBL25599785 | 0.89 | EGFR (0.77) | EGFRERBB2KDRBRAFCIT | |
| SCHEMBL17557987 | 0.89 | EGFR (0.70) | EGFRERBB2KDRBRAFCIT | |
| SCHEMBL641806 | 0.89 | EGFR (0.79) | EGFRERBB2KDRFLT4EPHB4 | |
| SCHEMBL4342528 | 0.89 | EGFR (0.79) | EGFRERBB2KDRFLT4EPHB4 | |
| SCHEMBL643422 | 0.89 | EGFR (0.79) | EGFRERBB2KDRFLT4EPHB4 | |
| SCHEMBL17558002 | 0.88 | EGFR (0.69) | EGFRERBB2KDRBRAFCIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093701-A1 | PLATINUM (II) COMPOUND HAVING TARGETING EFFECT AND DERIVATIVE THEREOF, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE | 东南大学 | 2023-06-01 | — | — | WO | disclosed |