Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163769 | 0.91 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL166306 | 0.85 | NAMPT (0.88) | NAMPT | |
| SCHEMBL164798 | 0.84 | NAMPT (0.79) | NAMPTCYP2C9 | |
| SCHEMBL161633 | 0.83 | NAMPT (0.78) | NAMPTCYP2C9 | |
| SCHEMBL165247 | 0.83 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL165579 | 0.83 | NAMPT (0.76) | NAMPTCYP2C9 | |
| SCHEMBL165631 | 0.83 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL31241518 | 0.82 | NAMPT (0.80) | NAMPTCYP2C9 | |
| Ammonia Solution, Strong SCHEMBL28918147 | 0.82 | NAMPT (0.76) | NAMPTCYP2C9 | |
| SCHEMBL165262 | 0.82 | NAMPT (0.80) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031196-A1 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL] AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |