Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CCNK | O75909 | 3/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 4/20 | 0.36 |
| ▸ | CCNH | P51946 | 4/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204169 | 1.00 | CDK2 (0.40) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL24087388 | 0.93 | CCNK (0.49) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL29509168 | 0.93 | CCNK (0.49) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25600726 | 0.93 | CDK2 (0.39) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL30204074 | 0.93 | CDK2 (0.39) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL25600739 | 0.90 | CDK2 (0.37) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL30204035 | 0.90 | CDK2 (0.37) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL30203959 | 0.89 | CCNK (0.43) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL30203949 | 0.83 | CDK7 (0.42) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL30204091 | 0.82 | CDK2 (0.42) | CDK2CCNKCDK12CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |