SCHEMBL25601331

SCHEMBL25601331

O=C1CCC(c2noc3c4c(ccc23)CNC4)C(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.49
DDB1 Q16531 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25601340 0.93 DDB1 (0.44) CRBNDDB1
SCHEMBL25601339 0.91 DDB1 (0.42) CRBNDDB1
SCHEMBL25601341 0.87 DDB1 (0.40) CRBNDDB1
SCHEMBL25601332 0.87 DDB1 (0.42) CRBNDDB1
SCHEMBL25601346 0.84 DDB1 (0.41) CRBNDDB1
SCHEMBL25601335 0.83 DDB1 (0.41) CRBNDDB1
SCHEMBL25817824 0.83 CRBN (0.45) CRBNDDB1
SCHEMBL25601343 0.82 DDB1 (0.40) CRBNDDB1
SCHEMBL25598692 0.82 DDB1 (0.41) CRBNDDB1
SCHEMBL25601359 0.81 CRBN (0.41) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed
WO-2023088406-A1 FUSED IMIDE DERIVATIVE 正大天晴药业集团股份有限公司 2023-05-25 WO disclosed