Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26782953 | 0.92 | RAF1 (0.56) | RAF1BRAF | |
| SCHEMBL26782937 | 0.91 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL30236468 | 0.83 | RAF1 (0.59) | RAF1BRAF | |
| SCHEMBL30237228 | 0.83 | RAF1 (0.59) | RAF1BRAF | |
| SCHEMBL30236487 | 0.83 | RAF1 (0.59) | RAF1BRAF | |
| SCHEMBL25591629 | 0.80 | ABL1 (0.55) | RAF1BRAF | |
| SCHEMBL26783122 | 0.80 | ABL1 (0.55) | RAF1BRAF | |
| SCHEMBL26783174 | 0.80 | BRAF (0.52) | RAF1BRAF | |
| SCHEMBL30291681 | 0.79 | RAF1 (0.74) | RAF1BRAF | |
| SCHEMBL22488531 | 0.79 | RAF1 (0.74) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023108103-A1 | RAF KINASE INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2023-06-15 | — | — | WO | disclosed |