Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558065 | 0.89 | UNG (0.41) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL16762586 | 0.84 | TRIM24 (0.46) | NOTUMUSP30DRD2DRD4NAMPT | |
| SCHEMBL2556279 | 0.84 | TRIM24 (0.46) | NOTUMUSP30DRD2DRD4NAMPT | |
| SCHEMBL17784836 | 0.83 | NOTUM (0.64) | MTNR1AMTNR1BNOTUMCNR1PTGDR2 | |
| SCHEMBL1800356 | 0.83 | NOTUM (0.64) | MTNR1AMTNR1BNOTUMCNR1PTGDR2 | |
| SCHEMBL29951119 | 0.83 | PIM1 (0.49) | MTNR1AMTNR1BDRD2 | |
| SCHEMBL15212339 | 0.82 | NOTUM (0.58) | MTNR1AMTNR1BNOTUMSCD5USP30 | |
| SCHEMBL23387205 | 0.79 | NOTUM (0.67) | MTNR1AMTNR1BNOTUMUSP30DRD2 | |
| SCHEMBL23387210 | 0.79 | NOTUM (0.67) | MTNR1AMTNR1BNOTUMPTGDR2 | |
| SCHEMBL23387206 | 0.79 | NOTUM (0.67) | MTNR1AMTNR1BNOTUMUSP30DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |