Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.82 |
| ▸ | LCK | P06239 | 18/20 | 0.82 |
| ▸ | EGFR | P00533 | 9/20 | 0.82 |
| ▸ | BTK | Q06187 | 6/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25606430 | 0.94 | JAK3 (0.86) | JAK3LCKEGFRBTK | |
| SCHEMBL25606431 | 0.93 | JAK3 (0.81) | JAK3LCKEGFRBTK | |
| SCHEMBL25606718 | 0.92 | JAK3 (0.79) | JAK3LCKEGFRBTK | |
| SCHEMBL21855246 | 0.91 | JAK3 (0.74) | JAK3LCKEGFRBTK | |
| SCHEMBL20867721 | 0.91 | JAK3 (0.89) | JAK3LCKEGFRBTK | |
| SCHEMBL29871796 | 0.90 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16763889 | 0.90 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16763891 | 0.90 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL24891001 | 0.90 | JAK3 (0.88) | JAK3LCKEGFRBTK | |
| SCHEMBL21855176 | 0.90 | JAK3 (0.87) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |