Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.61 |
| ▸ | LCK | P06239 | 17/20 | 0.61 |
| ▸ | BTK | Q06187 | 5/20 | 0.61 |
| ▸ | EGFR | P00533 | 9/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855409 | 0.95 | JAK3 (0.65) | JAK3LCKBTKEGFR | |
| SCHEMBL21946793 | 0.93 | JAK3 (0.71) | JAK3LCKBTKEGFR | |
| SCHEMBL29931224 | 0.93 | JAK3 (0.71) | JAK3LCKBTKEGFR | |
| SCHEMBL25603497 | 0.90 | JAK3 (0.62) | JAK3LCKBTKEGFR | |
| SCHEMBL25606268 | 0.89 | JAK3 (0.71) | JAK3LCKBTKEGFR | |
| SCHEMBL21946733 | 0.88 | JAK3 (0.64) | JAK3LCKBTKEGFR | |
| SCHEMBL21946343 | 0.88 | JAK3 (0.58) | JAK3LCKBTKEGFR | |
| SCHEMBL30011108 | 0.86 | JAK3 (0.61) | JAK3LCKBTKEGFR | |
| SCHEMBL28642834 | 0.86 | JAK3 (0.60) | JAK3LCKBTKEGFR | |
| SCHEMBL24926138 | 0.85 | JAK3 (0.79) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |