Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 18/20 | 0.64 |
| ▸ | BTK | Q06187 | 10/20 | 0.64 |
| ▸ | LCK | P06239 | 16/20 | 0.63 |
| ▸ | EGFR | P00533 | 9/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18884597 | 0.92 | JAK3 (0.71) | JAK3BTKLCKEGFR | |
| SCHEMBL25606965 | 0.89 | JAK3 (0.67) | JAK3BTKLCKEGFR | |
| SCHEMBL18884500 | 0.88 | LCK (0.77) | JAK3BTKLCKEGFR | |
| SCHEMBL21946711 | 0.88 | JAK3 (0.72) | JAK3BTKLCKEGFR | |
| SCHEMBL18884583 | 0.88 | JAK3 (0.66) | JAK3BTKLCKEGFR | |
| SCHEMBL18884529 | 0.87 | JAK3 (0.82) | JAK3BTKLCKEGFR | |
| SCHEMBL31039881 | 0.87 | JAK3 (0.73) | JAK3BTKLCKEGFR | |
| SCHEMBL21946364 | 0.87 | JAK3 (0.73) | JAK3BTKLCKEGFR | |
| SCHEMBL18884534 | 0.87 | JAK3 (0.72) | JAK3BTKLCKEGFR | |
| SCHEMBL16802091 | 0.87 | LCK (0.82) | JAK3BTKLCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |