Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559746 | 0.92 | TRPV1 (0.39) | ESR1IDO1TDO2MAPK14MAPK13 | |
| SCHEMBL2561033 | 0.91 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11ADORA2A | |
| SCHEMBL2551849 | 0.90 | IDO1 (0.40) | ESR1IDO1TDO2MPIFAAH | |
| SCHEMBL15332463 | 0.90 | MAPK14 (0.32) | ESR1IDO1TDO2MAPK14MAPK13 | |
| SCHEMBL15333169 | 0.89 | MAPK14 (0.37) | IDO1TDO2MAPK14MAPK13MAPK12 | |
| SCHEMBL15330137 | 0.88 | ESR1 (0.39) | ESR1IDO1TDO2MAPK14FAAH | |
| SCHEMBL15330684 | 0.88 | ESR1 (0.39) | ESR1IDO1TDO2MAPK14MAPK13 | |
| SCHEMBL15331817 | 0.88 | IDO1 (0.36) | ESR1IDO1TDO2MAPK14MAPK13 | |
| SCHEMBL2557819 | 0.87 | IDO1 (0.42) | ESR1IDO1TDO2FAAHMGLL | |
| SCHEMBL2557976 | 0.86 | IDO1 (0.39) | ESR1IDO1TDO2MAPK14MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |