SCHEMBL2560895

SCHEMBL2560895

CCC[C@H](N)c1cccc(C=O)n1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 6/20 0.55
SLC10A1 Q14973 1/20 0.33
CCR1 P32246 1/20 0.32
TERT O14746 5/20 0.31
SCN10A Q9Y5Y9 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15332216 1.00 IRAK4 (0.55) IRAK4SLC10A1CCR1TERTSCN10A
SCHEMBL2557836 0.91 IRAK4 (0.47) IRAK4SLC10A1CCR1TERT
SCHEMBL15333025 0.91 IRAK4 (0.47) IRAK4SLC10A1CCR1TERT
SCHEMBL15330138 0.87 IRAK4 (0.43) IRAK4SLC10A1CCR1TERTALDH1A1
SCHEMBL2556237 0.87 IRAK4 (0.43) IRAK4SLC10A1CCR1TERTALDH1A1
SCHEMBL20578748 0.81 IRAK4 (0.39) IRAK4SLC10A1CCR1TERTALDH1A1
SCHEMBL20578749 0.81 IRAK4 (0.39) IRAK4SLC10A1CCR1TERTALDH1A1
SCHEMBL15332535 0.81 IRAK4 (0.39) IRAK4SLC10A1CCR1TERTALDH1A1
SCHEMBL15332211 0.80 IRAK4 (0.38) IRAK4SLC10A1CCR1TERT
SCHEMBL15331695 0.80 IRAK4 (0.38) IRAK4SLC10A1CCR1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed