Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220192 | 0.95 | KMT2A (0.55) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL21226359 | 0.89 | APP (0.46) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL23134972 | 0.89 | APP (0.46) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL18220188 | 0.87 | APP (0.51) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL18220184 | 0.87 | APP (0.50) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL25610090 | 0.86 | APP (0.46) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17099866 | 0.85 | APP (0.55) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17099870 | 0.85 | APP (0.55) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17099878 | 0.85 | APP (0.55) | APPALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL24075821 | 0.85 | APP (0.55) | APPALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |