Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 4/20 | 0.32 |
| ▸ | CTSB | P07858 | 4/20 | 0.32 |
| ▸ | CTSS | P25774 | 4/20 | 0.32 |
| ▸ | CTSK | P43235 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220197 | 0.89 | APP (0.42) | APPDRD2DRD3KCNH2TSHR | |
| SCHEMBL17120836 | 0.87 | APP (0.34) | APPDRD2DRD3KCNH2CTSL | |
| SCHEMBL18220224 | 0.85 | APP (0.34) | APPDRD2DRD3KCNH2CTSL | |
| SCHEMBL17120807 | 0.83 | APP (0.37) | APPDRD2DRD3KCNH2ABL1 | |
| SCHEMBL17120810 | 0.83 | APP (0.37) | APPDRD2DRD3KCNH2ABL1 | |
| SCHEMBL25610261 | 0.83 | APP (0.34) | APPDRD2DRD3KCNH2CA1 | |
| SCHEMBL18220206 | 0.83 | APP (0.44) | APPDRD2DRD3KCNH2CTSL | |
| SCHEMBL23134879 | 0.82 | APP (0.34) | APPDRD2DRD3CTSLCTSB | |
| SCHEMBL23134917 | 0.82 | APP (0.36) | APPSLC16A3SLC16A1CSF1RMAPT | |
| SCHEMBL17120651 | 0.81 | APP (0.32) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |