Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.55 |
| ▸ | GSK3B | P49841 | 13/20 | 0.55 |
| ▸ | WNT1 | P04628 | 6/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602322 | 0.88 | GSK3B (0.70) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL30481303 | 0.88 | GSK3B (0.70) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL25612077 | 0.84 | GSK3B (0.56) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL31165742 | 0.84 | DYRK1A (0.56) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL25602324 | 0.84 | DYRK1A (0.56) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL31501380 | 0.82 | GSK3B (0.61) | DYRK1AGSK3BWNT1MKNK1CDK5 | |
| SCHEMBL25602457 | 0.82 | GSK3B (0.61) | DYRK1AGSK3BWNT1MKNK1CDK5 | |
| SCHEMBL25610793 | 0.80 | GSK3B (0.53) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL25263375 | 0.80 | GSK3B (0.56) | DYRK1AGSK3BWNT1MKNK1ABL1 | |
| SCHEMBL31501331 | 0.79 | DYRK1A (0.49) | DYRK1AGSK3BWNT1MKNK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |