Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 7/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | WNT1 | P04628 | 5/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25611490 | 0.85 | USP30 (0.49) | ABL1USP30GSK3BDYRK1AWNT1 | |
| SCHEMBL25611374 | 0.85 | DYRK1A (0.46) | ABL1USP30GSK3BDYRK1AWNT1 | |
| SCHEMBL25610793 | 0.83 | GSK3B (0.53) | ABL1CDK2CCNE1CDK5GSK3B | |
| SCHEMBL25613669 | 0.81 | ABL1 (0.46) | ABL1USP30GSK3BDYRK1AWNT1 | |
| SCHEMBL25263375 | 0.79 | GSK3B (0.56) | ABL1CDK2CCNE1CDK5GSK3B | |
| SCHEMBL25611113 | 0.78 | CDK2 (0.43) | ABL1CDK2CCNE1CDK5GSK3B | |
| SCHEMBL4307403 | 0.78 | LIMK1 (0.51) | ABL1CDK2CCNE1CDK5GSK3B | |
| SCHEMBL25611231 | 0.77 | GSK3B (0.46) | ABL1CDK2CCNE1CDK5GSK3B | |
| SCHEMBL31165742 | 0.77 | DYRK1A (0.56) | ABL1CDK2CCNE1CDK5GSK3B | |
| SCHEMBL25602324 | 0.77 | DYRK1A (0.56) | ABL1CDK2CCNE1CDK5GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |