Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 6/20 | 0.32 |
| ▸ | AHCY | P23526 | 3/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADA | P00813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519305 | 0.84 | ADORA2A (0.33) | ADORA2AKDRAHCYPI4KAPI4K2B | |
| SCHEMBL25611841 | 0.78 | NPC1 (0.33) | — | |
| SCHEMBL21913198 | 0.77 | KDR (0.30) | KDR | |
| SCHEMBL25611830 | 0.72 | — | — | |
| SCHEMBL25611849 | 0.69 | NPC1 (0.34) | — | |
| SCHEMBL20375123 | 0.68 | LIMK1 (0.32) | — | |
| SCHEMBL21393838 | 0.65 | MAPT (0.44) | KDRADORA3 | |
| SCHEMBL19999905 | 0.61 | — | — | |
| SCHEMBL1485758 | 0.61 | — | — | |
| SCHEMBL24514193 | 0.61 | TLR8 (0.38) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102228-A1 | HETEROCYCLIC COMPOPUNDS AS GCN2 AND PERK KINASE INHIBITORS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2023-06-08 | — | — | WO | disclosed |