Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.54 |
| ▸ | WNT1 | P04628 | 8/20 | 0.54 |
| ▸ | ABL1 | P00519 | 5/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25611371 | 0.95 | GSK3B (0.57) | GSK3BDYRK1AWNT1ABL1CNR2 | |
| SCHEMBL25612495 | 0.94 | GSK3B (0.52) | GSK3BDYRK1AWNT1ABL1HDAC3 | |
| SCHEMBL31271929 | 0.88 | GSK3B (0.54) | GSK3BDYRK1AWNT1ABL1HDAC3 | |
| SCHEMBL25609003 | 0.88 | GSK3B (0.54) | GSK3BDYRK1AWNT1ABL1HDAC3 | |
| SCHEMBL25611490 | 0.86 | USP30 (0.49) | GSK3BDYRK1AWNT1ABL1USP30 | |
| SCHEMBL25612330 | 0.86 | GSK3B (0.54) | GSK3BDYRK1AWNT1ABL1MKNK1 | |
| SCHEMBL25612408 | 0.85 | GSK3B (0.51) | GSK3BDYRK1AWNT1ABL1USP30 | |
| SCHEMBL25613163 | 0.85 | GSK3B (0.55) | GSK3BDYRK1AWNT1ABL1MKNK1 | |
| SCHEMBL31271917 | 0.84 | GSK3B (0.57) | GSK3BDYRK1AWNT1ABL1MKNK1 | |
| SCHEMBL25609004 | 0.84 | GSK3B (0.57) | GSK3BDYRK1AWNT1ABL1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |