Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398665 | 1.00 | EPHX2 (0.48) | EPHX2HPGDNAMPTLOXL2EPHX1 | |
| SCHEMBL25639850 | 0.95 | EPHX2 (0.43) | EPHX2HPGDNAMPTLOXL2EPHX1 | |
| SCHEMBL30399087 | 0.93 | EPHX2 (0.43) | EPHX2HPGDNAMPTEPHX1ALDH1A1 | |
| SCHEMBL25614255 | 0.93 | EPHX2 (0.43) | EPHX2HPGDNAMPTEPHX1ALDH1A1 | |
| SCHEMBL25638931 | 0.87 | EPHX1 (0.42) | HPGDNAMPTLOXL2EPHX1MAPT | |
| SCHEMBL25638932 | 0.87 | EPHX1 (0.42) | HPGDNAMPTLOXL2EPHX1MAPT | |
| SCHEMBL30398988 | 0.86 | EPHX2 (0.41) | EPHX2HPGDNAMPTEPHX1MAPT | |
| SCHEMBL25613761 | 0.86 | EPHX2 (0.41) | EPHX2HPGDNAMPTEPHX1MAPT | |
| SCHEMBL30398893 | 0.84 | EPHX2 (0.48) | EPHX2HPGDNAMPTEPHX1MAPT | |
| SCHEMBL25615170 | 0.84 | EPHX2 (0.48) | EPHX2HPGDNAMPTEPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091554-A1 | NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS | ICAGEN, LLC (US) | 2023-05-25 | — | — | WO | disclosed |