Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811694 | 0.83 | GRM5 (0.31) | — | |
| SCHEMBL29176201 | 0.83 | CYP1A2 (0.30) | CYP1A2CYP2C9 | |
| SCHEMBL30811735 | 0.83 | CYP1A2 (0.30) | CYP1A2CYP2C9 | |
| SCHEMBL14299558 | 0.78 | CYP2E1 (0.48) | CYP3A4CYP2A6CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL25614497 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30811647 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL25614466 | 0.76 | GRM5 (0.31) | — | |
| SCHEMBL30463031 | 0.76 | CYP3A4 (0.61) | CYP3A4CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL25614598 | 0.75 | KDM4E (0.40) | LMNAMAPTNOTUMMEN1KMT2A | |
| SCHEMBL25614363 | 0.73 | CYP2A6 (0.41) | CYP2A6CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |