Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 14/20 | 0.69 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25617594 | 0.96 | TIPARP (0.67) | TIPARPROCK2NAMPTMAOAMAOB | |
| SCHEMBL21520888 | 0.90 | TIPARP (0.78) | TIPARP | |
| SCHEMBL21521185 | 0.86 | TIPARP (0.73) | TIPARP | |
| SCHEMBL25617114 | 0.86 | TIPARP (0.59) | TIPARPROCK2NAMPT | |
| SCHEMBL25617605 | 0.84 | TIPARP (0.75) | TIPARPROCK2 | |
| SCHEMBL21520876 | 0.82 | TIPARP (0.70) | TIPARP | |
| SCHEMBL30255578 | 0.82 | TIPARP (1.00) | TIPARPROCK2 | |
| SCHEMBL21522221 | 0.82 | TIPARP (1.00) | TIPARPROCK2 | |
| SCHEMBL25617043 | 0.82 | TIPARP (0.76) | TIPARPCHRM4 | |
| SCHEMBL25617526 | 0.82 | TIPARP (0.76) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192664-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192664-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | PARP2, PARP1, PARP4 | TIPARP 152/4885ROCK2 1862/4885NAMPT 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.