Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | SCN1A | P35498 | 2/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25620024 | 0.95 | MEN1 (0.55) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25620021 | 0.87 | MEN1 (0.61) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25620014 | 0.83 | KMT2A (0.53) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25620007 | 0.83 | MEN1 (0.50) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25619985 | 0.82 | MAPT (0.52) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL7227329 | 0.82 | HPGD (0.49) | CYP1A2MAPTLMNAHPGDHSD17B10 | |
| SCHEMBL25619977 | 0.81 | MEN1 (0.60) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25621664 | 0.80 | KMT2A (0.56) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25622735 | 0.80 | MEN1 (0.58) | MEN1KMT2ACYP1A2SCN1ASCN2A | |
| SCHEMBL25619974 | 0.80 | KMT2A (0.58) | MEN1KMT2ACYP1A2SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183169-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN DRUG | Sichuan Academy Of Medical Sciences · Sichuan Provincial People's Hospital (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20230183169-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN DRUG | Sichuan Academy Of Medical Sciences · Sichuan Provincial People's Hospital (CN) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183169-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN DRUG | NOTUM, BYSL, TYR | MEN1 2637/4885KMT2A 2785/4885CYP1A2 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.