⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25617769 | 0.95 | KCNH2 (0.33) | — | |
| SCHEMBL26287097 | 0.92 | — | — | |
| SCHEMBL2708356 | 0.85 | — | — | |
| SCHEMBL888707 | 0.85 | — | — | |
| SCHEMBL25617760 | 0.82 | — | — | |
| SCHEMBL10118833 | 0.81 | — | — | |
| SCHEMBL9980164 | 0.77 | — | — | |
| SCHEMBL890139 | 0.77 | — | — | |
| SCHEMBL2707426 | 0.76 | — | — | |
| SCHEMBL10141119 | 0.72 | KCNH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286947-A1 | COMPLEMENT FACTOR B INHIBITOR, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND USE THEREOF | SHANGHAI MEIYUE BIOTECH DEVELOPMENT CO. LTD. (CN) | 2023-09-14 | — | — | US | disclosed |
| US-20230286947-A1 | COMPLEMENT FACTOR B INHIBITOR, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND USE THEREOF | SHANGHAI MEIYUE BIOTECH DEVELOPMENT CO. LTD. (CN) | 2023-09-14 | — | — | US | disclosed |
| EP-4194451-A1 | COMPLEMENT FACTOR B INHIBITOR, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023072197-A1 | PIPERIDINYL INDOLE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | HANSOH BIO LLC (US) | 2023-05-04 | — | — | WO | disclosed |