Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097991 | 0.91 | HSD17B10 (0.57) | HSD17B10KDM4EPOLBPTGDR2MEN1 | |
| SCHEMBL2562353 | 0.88 | KDM4E (0.52) | HSD17B10KDM4EPOLBLMNATP53 | |
| SCHEMBL2562856 | 0.88 | HSD17B10 (0.61) | HSD17B10KDM4EPOLBLMNAPTGDR2 | |
| SCHEMBL9152146 | 0.83 | SLC1A5 (0.57) | HSD17B10KDM4EPOLBLMNAPTGDR2 | |
| SCHEMBL9148385 | 0.82 | SLC1A5 (0.56) | HSD17B10KDM4EPOLBLMNAPTGDR2 | |
| SCHEMBL2560429 | 0.82 | HSD17B10 (0.51) | HSD17B10PTGDR2CAMK2A | |
| SCHEMBL154368 | 0.81 | HSD17B10 (0.68) | HSD17B10KDM4EPOLBPTGDR2MEN1 | |
| SCHEMBL2561912 | 0.81 | KDM4E (0.49) | HSD17B10KDM4EPTGDR2MEN1ALDH1A1 | |
| SCHEMBL5107368 | 0.80 | HSD17B10 (0.54) | HSD17B10KDM4EPOLBPTGDR2MEN1 | |
| SCHEMBL6947536 | 0.80 | SLC6A4 (0.59) | KDM4EPOLBALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |