Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052343 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1F2GLA | |
| SCHEMBL25273063 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1F2GLA | |
| SCHEMBL31052382 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1F2GLA | |
| SCHEMBL25219336 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1F2GLA | |
| SCHEMBL31052289 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1F2GLA | |
| SCHEMBL25273245 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1F2GLA | |
| SCHEMBL25263643 | 0.84 | CYP11B1 (0.33) | CYP11B1CYP11B2CBFBALDH1A1TP53 | |
| SCHEMBL31052344 | 0.84 | CYP11B1 (0.33) | CYP11B1CYP11B2CBFBALDH1A1TP53 | |
| SCHEMBL25622024 | 0.83 | TLR8 (0.39) | CYP11B1CYP11B2S1PR1 | |
| SCHEMBL25255506 | 0.83 | CYP11B1 (0.32) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |