⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2792297 | 1.00 | — | — | |
| SCHEMBL27523976 | 0.96 | PARP1 (0.30) | — | |
| SCHEMBL32681392 | 0.93 | — | — | |
| SCHEMBL30999499 | 0.93 | — | — | |
| SCHEMBL29581431 | 0.93 | — | — | |
| SCHEMBL29835025 | 0.93 | — | — | |
| SCHEMBL12501828 | 0.93 | — | — | |
| SCHEMBL2132650 | 0.93 | — | — | |
| Water SCHEMBL18642501 | 0.93 | — | — | |
| SCHEMBL6345413 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | claimed |
| CN-109438482-A | A kind of double-fluoquinolone base oxadiazoles carbamide derivative and its preparation method and application containing Rufloxacin | 郑州工业应用技术学院 | 2019-03-08 | — | — | CN | claimed |
| CN-109400626-A | A kind of pair-fluoquinolone oxadiazoles ureas fleraxacin derivative and its preparation method and application | 郑州工业应用技术学院 | 2019-03-01 | — | — | CN | claimed |
| CN-109369674-A | A kind of double-fluoquinolone base oxadiazoles carbamide derivative and its preparation method and application containing lavo-ofloxacin | 郑州工业应用技术学院 | 2019-02-22 | — | — | CN | claimed |
| CN-108699048-A | Oxadiazolamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2018-10-23 | — | — | CN | claimed |
| US-20180273495-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-09-27 | — | — | US | claimed |
| EP-3362445-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2018-08-22 | — | — | EP | claimed |
| CN-108409682-A | A kind of chirality diazole and binaphthol derivative and its synthetic method | 华东师范大学 | 2018-08-17 | — | — | CN | claimed |
| WO-2017065473-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-04-20 | — | — | WO | claimed |
| CN-104725168-A | High power powdery ammonium nitrate explosive and preparation process thereof | Hongda mining industry co ltd | 2015-06-24 | — | — | CN | claimed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-121270536-A | 2-Substituted-1-H-indole oxadiazole amine derivative compound and preparation method and application thereof | 贵州大学 | 2026-01-06 | — | — | CN | disclosed |
| EP-3998260-B1 | SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2023-11-01 | — | — | EP | disclosed |
| EP-3827004-B1 | 4-(1,3,4-OXADIAZOLE-2-YL)PYRIDINE-2(1H)-ONE DERIVATIVES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS FOR THE TREATMENT OF E.G. INFECTIONS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-10-11 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-5185358-A | Anticholesterol agents | WARNER-LAMBERT CO. (US) | 1993-02-09 | — | — | US | disclosed |
| CN-1053429-A | INDOLE-SUBSTITUTED FIVE-MEMBERED HETEROAROMATIC COMPOUNDS | MERCK SHARP & DOHME (GB) | 1991-07-31 | — | — | CN | disclosed |
| CN-87102972-A | Treatment senile dementia oxadiazoles useful | — | 1987-11-18 | — | — | CN | disclosed |