Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 10/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624792 | 0.91 | HDAC6 (0.61) | HDAC6MAOBHRH3ACVR1CNR2 | |
| SCHEMBL25624795 | 0.87 | HRH3 (0.44) | HDAC6MAOBHRH3TLR9TLR7 | |
| SCHEMBL25625025 | 0.82 | HDAC6 (0.59) | HDAC6MAOBCNR2TLR9TLR7 | |
| SCHEMBL15676237 | 0.79 | HDAC6 (0.60) | HDAC6MAOBCNR2TLR9KDM4E | |
| SCHEMBL23327551 | 0.78 | HDAC6 (0.59) | HDAC6MAOBCNR2TLR9KDM4E | |
| SCHEMBL25625116 | 0.78 | HDAC6 (0.66) | HDAC6MAOBACVR1CNR2TLR9 | |
| SCHEMBL1675284 | 0.78 | HDAC6 (0.65) | HDAC6MAOBCNR2 | |
| SCHEMBL1675467 | 0.76 | HDAC6 (0.63) | HDAC6MAOB | |
| SCHEMBL30771676 | 0.76 | MAOB (0.44) | MAOBHRH3CNR2KDM4E | |
| SCHEMBL1675444 | 0.72 | HDAC6 (0.79) | HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109745-A1 | SMALL-MOLECULE PROBE FOR IMAGING OF α-SYNUCLEIN AGGREGATE | 复旦大学 | 2023-06-22 | — | — | WO | disclosed |